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Biological Sequence Databases on the HPC

Some of the most common biological sequence databases are available on the HPC for you to use with tools like BLAST. Below you can find the list of them, their location on the system, and the last time they were updated.

We endeavor to keep this list updated as the One True List™.

Name Comments Updated¹ Database Location
NCBI nr/nt nucleotide collection 2018-11-24 /export/data/bio/ncbi/blast/db
NCBI nr/nt protein collection 2018-08-16 /export/data/bio/ncbi/blast/db
UniProt's UniProtKB/Swiss-Prot Manually curated, most reliable ? /export/data/bio/uniprot/blast/db
UniProt's UniProtKB/TrEMBL Automated curation ? /export/data/bio/uniprot/blast/db
UniProt's UniRef100 ? /export/data/bio/uniprot/blast/db

Using These Databases

To use these databases you generally need to set an environment variable pointing to the location of the database before running your program. For example, to use nt with NCBI blastn:

$ export BLASTDB=/export/data/bio/ncbi/blast/db
$ blastn -db nt -query file.seq -out blast.out


¹ Use the following to determine the date of a BLAST database: /export/apps/blast/2.7.1+/bin/blastdbcmd -info -db nt | grep Date

biological-databases.1552508928.txt.gz · Last modified: 2019/03/13 20:28 by aorth