BCFtools implements utilities for variant calling (in conjunction with SAMtools) and manipulating VCF and BCF files. The program is intended to replace the Perl-based tools from vcftools.

• Latest Version: 1.6
• Added: September, 2015
• Updated: December, 2017
• Link: https://samtools.github.io/bcftools

See versions of bcftools which are available:

$ module avail bcftools

Load one version into your environment:

$ module load bcftools/1.6

Notes from the sysadmin during installation:

$ cd /tmp
$ wget https://github.com/samtools/bcftools/releases/download/1.6/bcftools-1.6.tar.bz2
$ tar xf bcftools-1.6.tar.bz2 
$ cd bcftools-1.6
$ ./configure --prefix=/export/apps/bcftools/1.6
$ make all all-htslib
$ sudo mkdir /export/apps/bcftools/1.6
$ sudo chown aorth /export/apps/bcftools/1.6
$ make install install-htslib
$ sudo chown -R root:root /export/apps/bcftools/1.6