Table of Contents

htslib

htslib is an implementation of a unified C library for accessing common file formats, such as SAM, CRAM and VCF, used for high-throughput sequencing data, and is the core library used by samtools and bcftools

Information

Usage

See versions which are available:

$ module avail htslib

Load one version into your environment and run it:

$ module load htslib/1.15.1
$ tabix
$ bgzip

Installation

Notes from the sysadmin during installation:

$ cd /tmp
$ wget https://github.com/samtools/htslib/releases/download/1.15.1/htslib-1.15.1.tar.bz2
$ tar xf htslib-1.15.1.tar.bz2
$ cd htslib-1.15.1
$ ./configure --enable-plugins --enable-libcurl --prefix=/export/apps/htslib/1.15.1
$ make
$ sudo mkdir -p /export/apps/htslib/1.15.1
$ sudo chown aorth /export/apps/htslib/1.15.1
$ make install
$ sudo chown -R root:root /export/apps/htslib/1.15.1

Note: as of 1.15.1 this was compiled on CentOS Stream 8