====== GROM-RD ====== Analyzes multiple biases in read coverage to detect CNVs in NGS data. To overcome a typical weakness of read depth (RD) methods, GROM-RD employs a CNV search using size-varying overlapping windows to improve breakpoint resolution. GROM-RD was able to improve RD sensitivity, specificity, and breakpoint accuracy compared to CNVnator and RDXplorer, the two most frequently used RD algorithms. Additionally, GROM-RD had a short run time that was relatively insensitive to read coverage indicating excellent scalability of the method for different datasets. ===== Information ===== * Version: 1.0 * Added: May, 2017 * Link: http://grigoriev.rutgers.edu/software/grom-rd/index.html ===== Usage ===== See which versions of grom-rd are available: $ module avail grom-rd Load groovy $ module load grom-rd/1.0 ===== Installation ====== Notes from the sysadmin during installation: $ cd /tmp $ wget http://grigoriev.rutgers.edu/software/grom-rd/GROM-RD_v1.0.tar.gz $ tar xf GROM-RD_v1.0.tar.gz $ cd GROM-RD_v1.0 $ make $ sudo mkdir -p /export/apps/grom-rd/1.0 $ sudo cp bin/GROM-RD /export/apps/grom-rd/1.0