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PolyPhen-2 (Polymorphism Phenotyping v2) is a software tool which predicts possible impact of amino acid substitutions on the structure and function of human proteins using straightforward physical and evolutionary comparative considerations.



See versions of polyphen which are available:

$ module avail polyphen

Load polyphen:

$ module load polyphen


Notes from the sysadmin during installation:

$ cd /tmp
$ wget -qO- | tar xzv
$ cd polyphen-2.2.2/
$ scl enable devtoolset-3 bash
$ module load perl/5.22.3
$ cpanm DBD::SQLite
$ sudo mkdir -p /export/apps/polyphen/2.2.2
$ sudo chown -R joguya:joguya /export/apps/polyphen/2.2.2
$ ./configure
$ make download
$ make
$ make install
$ cp -r . /export/apps/polyphen/2.2.2
$ sudo chown -R root:root /export/apps/polyphen/2.2.2
polyphen-software.1489062516.txt.gz · Last modified: 2017/03/09 15:28 by joguya