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| + | ====== hypo ====== | ||
| + | HyPo--a Hybrid Polisher-- utilises short as well as long reads within a single run to polish a long reads assembly of small and large genomes. It exploits unique genomic kmers to selectively polish segments of contigs using partial order alignment of selective read-segments. As demonstrated on human genome assemblies, Hypo generates significantly more accurate polished assembly in about one-third time with about half the memory requirements in comparison to contemporary widely used polishers like Racon. | ||
| + | ===== Information ===== | ||
| + | |||
| + | * Version: 1.0.3 | ||
| + | * Added: January, 2021 | ||
| + | * Link: https:// | ||
| + | |||
| + | ===== Usage ===== | ||
| + | |||
| + | See versions of hypo which are available: | ||
| + | < | ||
| + | |||
| + | Load one version into your environment and run it: | ||
| + | < | ||
| + | $ hypo</ | ||
| + | |||
| + | ===== Installation ====== | ||
| + | Notes from the sysadmin during installation: | ||
| + | |||
| + | < | ||
| + | $ git clone --recursive https:// | ||
| + | $ cd hypo | ||
| + | # Install a newer compiler for C++17 features in hypo | ||
| + | $ sudo yum install devtoolset-7-gcc devtoolset-7-gcc-gfortran devtoolset-7-libquadmath-devel devtoolset-7-gcc-c++ | ||
| + | $ scl enable devtoolset-7 bash | ||
| + | $ mkdir build | ||
| + | $ cd build | ||
| + | $ cmake3 -DCMAKE_BUILD_TYPE=Release .. | ||
| + | $ make -j4 | ||
| + | $ sudo mkdir -p / | ||
| + | $ sudo cp bin/hypo / | ||
| + | |||
| + | **Note:** I had to modify the CMakeLists.txt file to hard code our global htslib, see: https:// | ||