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bowtie1-software [2014/10/17 10:44]
joguya created
bowtie1-software [2014/10/17 10:47] (current)
joguya
Line 1: Line 1:
 ====== Bowtie ====== ====== Bowtie ======
   * Bowtie is an ultrafast, memory-efficient short read aligner. It aligns short DNA sequences (reads) to the human genome at a rate of over 25 million 35-bp reads per hour. Bowtie indexes the genome with a Burrows-Wheeler index to keep its memory footprint small: typically about 2.2 GB for the human genome (2.9 GB for paired-end).   * Bowtie is an ultrafast, memory-efficient short read aligner. It aligns short DNA sequences (reads) to the human genome at a rate of over 25 million 35-bp reads per hour. Bowtie indexes the genome with a Burrows-Wheeler index to keep its memory footprint small: typically about 2.2 GB for the human genome (2.9 GB for paired-end).
-  * +  * For reads longer than about 50 bp Bowtie 2 is generally faster, more sensitive, and uses less memory than Bowtie 1. For relatively short reads (e.g. less than 50 bp) Bowtie 1 is sometimes faster and/or more sensitive. 
 +  * There is no upper limit on read length in Bowtie 2. Bowtie 1 had an upper limit of around 1000 bp. 
 +  * [[http://​bowtie-bio.sourceforge.net/​bowtie2/​manual.shtml#​how-is-bowtie-2-different-from-bowtie-1| differences between Bowtie1 & Bowtie2]]
  
 ===== Bowtie v1.1.1 ===== ===== Bowtie v1.1.1 =====
bowtie1-software.txt · Last modified: 2014/10/17 10:47 by joguya