BCFtools implements utilities for variant calling (in conjunction with SAMtools) and manipulating VCF and BCF files. The program is intended to replace the Perl-based tools from vcftools.

• Latest Version: 1.3.1
• Added: September, 2015
• Updated: February, 2017
• Link: https://samtools.github.io/bcftools

$ module avail bcftools

Notes from the sysadmin during installation:

$ cd /tmp
$ wget -qO- https://github.com/samtools/bcftools/releases/download/1.3.1/bcftools-1.3.1.tar.bz2 | tar xjv
$ cd bcftools-1.3.1
$ scl enable devtoolset-3 bash
$ sudo mkdir /export/apps/bcftools/1.3.1
$ HTSDIR=/export/apps/htslib/1.3.2 make
$ make prefix=/export/apps/bcftools/1.3.1 install
$ sudo chown -R root:root /export/apps/bcftools/1.3.1